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生物通
27 天
综述:DDR1在肿瘤学中的新兴策略与转化进展
这篇综述系统阐述了盘状结构域受体1(DDR1)作为肿瘤治疗靶点的最新研究进展。作者详细解析了DDR1的结构特征、在多种癌症(如胰腺癌、乳腺癌、肝癌等)中通过调控ECM重塑、EMT、免疫微环境(TME)等机制促进肿瘤进展的作用,并综述了DDR1抑制剂(如单抗7rh ...
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