2024年5月28日 · UNIVERSE 25: John Calhoun crouches within his rodent utopia-turned-dystopia that, at its peak, housed approximately 2,200 mice. Calhoun was studying the breakdown of social bonds that occurs under extreme overcrowding, following up on his earlier discovery of the learned "behavioral sink" phenomenon in rats. 1

3 天之前 · Sex Differences in Neurological Research. Experts from the Women’s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.

ABOVE: A positive rapid test will yield two visible lines (middle) while a valid negative test will only show a single line in the control region (right) and an invalid test will show no control line (left). iStock, ASIFE V iral TikTok videos showing teenagers hacking rapid COVID-19 tests by inserting sodas and other acidic solutions into the tests’ inlet caused quite a stir in 2021 ...

Sternberg pondered about the underlying mechanism; he suspected that there must be a genetic hotspot for recombination located at the terminal ends of the linear genome to facilitate plasmid cyclization. 1. The genesis of Cre-loxP recombinationConsistent with his hypothesis, Sternberg’s experiments revealed a small fragment of P1 DNA at the end of …

2023年11月8日 · Like PCR, qPCR amplifies DNA using a DNA polymerase enzyme.This adds new nucleotides to the 3’-OH end of a short, single-stranded DNA segment, called a primer, which complements the template strand. 2 The reaction occurs in specialized thermal cyclers equipped with fluorometers that measure fluorescent signals, quantifying both relative and absolute DNA amounts when combined with reference ...

The Scientist’s Top 10 Innovations contest is back. This year we took nominations for cutting-edge products launched between January 2023 and July 2024. The results showcased emerging trends in basic, translational, and clinical research, and beyond. From fine-tuned updates to brand-new products ...

Welcome to Words for Nerds, our popular and addictive daily science word game. Think of it as science Wordle—a guessing jumble for every nerd, especially the busy life scientist looking to get a little break from the rigors of research. You have six chances to guess either a …

C re-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. 1,2 This works through two key components: a Cre recombinase and loxP sequence recognition sites. The Cre enzyme identifies pairs of loxP sites (arrowheads), which flank (flox) the DNA, and catalyzes reciprocal DNA recombination between the two sites to excise a small piece ...

2024年5月8日 · Upstream and Downstream Bioprocessing. Bioprocesses encompass a sequence of activities that facilitate biochemical changes, with upstream processing steps that prepare biomass and substrates for catalytic reactions, followed by downstream processing to handle the resulting materials. 1 To change the phase or composition of raw materials, most systems employ a series of methods called unit ...

2024年2月23日 · Tanuka Biswas is a science communication professional, with over a decade of experience in molecular biology, cancer biology, and content strategy. She earned her PhD in biomedical sciences at the University of Texas Health Science Center, with a focus on cancer biology. She is passionate about ...