自噬信号通路 | Cell Signaling Technology
Discover the autophagy pathway and its crucial role in cellular homeostasis. Learn more and uncover the mechanisms of cellular self-degradation here.
Autophagy Pathway - Cell Signaling Technology
Discover the autophagy pathway and its crucial role in cellular homeostasis. Learn more and uncover the mechanisms of cellular self-degradation here.
Autophagy pathway: Cellular and molecular mechanisms - PMC
Macroautophagy/autophagy is an essential, conserved self-eating process that cells perform to allow degradation of intracellular components, including soluble proteins, aggregated proteins, organelles, macromolecular complexes, and foreign bodies.
Autophagy: Regulator of cell death | Cell Death & Disease - Nature
2023年10月4日 · Autophagy is a complex self-degradation process involving the following key steps: ① Signaling pathways regulate the initiation of autophagy. AMPK inhibits the formation of the mTORC1...
Regulation mechanisms and signaling pathways of autophagy
Autophagy is upregulated in response to extra- or intracellular stress and signals such as starvation, growth factor deprivation, ER stress, and pathogen infection. Defective autophagy plays a significant role in human pathologies, including cancer, neurodegeneration, and …
Autophagy Research Resources | Cell Signaling Technology
Overview of autophagy signaling, antibodies and related reagents, interactive pathway diagrams, and technical resources for autophagy research.
The autophagy pathway and its key regulators - ScienceDirect
2022年1月1日 · In this chapter, we first summarize the core autophagy machinery that is essential for the formation of autophagosomes and autolysosomes. We then describe intracellular signaling pathways and key relevant molecules involved in the regulation of autophagy. Finally, target-specific autophagy (selective autophagy) will be discussed.
An overview of autophagy: Mechanism, regulation and
2021年3月1日 · Autophagy is a complex regulation process involving many upstream signal regulation pathways (figure 6). Today, the most studied pathways for regulating autophagy are mainly mTOR and PI3K pathways, whereas other regulatory signals play a role directly or indirectly through these two pathways.
Autophagy and signaling: their role in cell survival and cell death
2005年10月25日 · Macroautophagy is activated by signaling pathways that also control apoptosis. The aim of this review is to discuss the signaling pathways that control macroautophagy during cell survival and...
Autophagy Signaling Pathway - Bio-Techne
Individual ATG proteins and ATG-complexes support specific steps in the dynamic process of autophagy. The formation of a double membrane vesicle for the entrapment and delivery of cytosolic content to lysosomes is the hallmark of autophagy. Formation of the mature organelle or autolysosome involves a sequence of coordinated events.