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    Mesolimbic pathway - Wikipedia

    • The mesolimbic pathway is a collection of dopaminergic (i.e., dopamine-releasing) neurons that project from the ventral tegmental area (VTA) to the ventral striatum, which includes the nucleus accumbens (NAcc) and olfactory tubercle. It is one of the component pathways of the medial forebrain bundle, which is a set of neural pathways that mediate brain st… 展开

    Overview

    The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain. The pathway c… 展开

    Function

    The mesolimbic pathway regulates incentive salience, motivation, reinforcement learning, and fear, among other cognitive processes.
    The mesolimbic pathway is involved in motivational cognition. … 展开

    Clinical significance

    The mesolimbic pathway and a specific set of the pathway's output neurons (e.g. D1-type medium spiny neurons within the nucleus accumbens) play a central role in the neurobiology of addiction. Drug addiction is an illness caus… 展开

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