Used for neutralising systemic envenoming by members of the Australian taipan snake group. It is made from horse IgG. Each ampoule contains 12,000 units of neutralising capacity against the target venoms. Average volume per ampoule is 43-50mL. The immunising venom is from the common taipan.

Based on the median lethal dose value in mice, the venom of the inland taipan is by far the most toxic of any snake – much more so than even that of sea snakes [11] [12] [13] – and it has the most toxic venom of any reptile when tested on human heart cell culture.

2023年9月17日 · Its venom works fast, attacking the heart, the blood stream and the nervous system, causing paralysis and convulsions while the patient's skin turns black. European settlers thought the species was a myth until 1933 when naturalist Donald Thompson was led to a live taipan by local Indigenous people on Cape York.

Inland Taipan Profile. The inland taipan (Oxyuranus microlepidotus) is the most venomous snake in the world. The venom of one bite is strong enough to kill 100 men. They are native to central and eastern Australia in dry areas and are commonly known as the western taipan, the small-scaled snake, or the fierce snake. Inland Taipan Facts Overview

2020年11月3日 · Taipan antivenom (equine IgG Fab) can be used to treat envenomation from the Taipan snakes in Australia and Papua New Guinea, these include the Costal Taipan, Papuan Taipan and the small-scaled or fierce snake. Indication: Clinical evidence of envenomation including neurotoxicity

Antivenoms manufactured by bioCSL Limited (Australia) and Instituto Clodomiro Picado (Costa Rica) against the venom of the taipan snakes (Oxyuranus scutellatus) from Australia and Papua New Guinea (PNG), respectively, were compared using antivenomics, an analytical approach that combines proteomics with immunoaffinity chromatography.

The recommended treatment for taipan envenomation is Seqirus (bioCSL) taipan antivenom and rapid administration is critical, as both VICC and pre-synaptic neurotoxicity are life-threatening and irreversible if allowed to progress. Patients may face extended stays in hospital, including the need for mechanical ventilation, if treatment is delayed.

The results of the current study indicate that taipan antivenom, raised against O. scutellatus venom, is effective, in vitro, against the neurotoxic effects of venom from the Papuan and coastal taipans, as well as the presynaptic effects of venom from the inland taipan.

Taipan antivenom is given to people who become ill from venom after being bitten by a taipan snake. For more information, see Section 1. Why am I using Taipan Antivenom? in the full CMI. 2. What should I know before being given Taipan Antivenom?

TAIPAN ANTIVENOM is prepared from the plasma of horses immunised with the venom of the coastal taipan snake (Oxyuranus scutellatus). Each vial contains 12,000 units of antivenom which has been standardised to neutralise in vitro, the average yield of venom from the taipan.