- Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured neurons and along nociceptive and descending modulatory pathways in the central nervous system.Author: Steven P Cohen, Jianren MaoPublish Year: 2014pubmed.ncbi.nlm.nih.gov/24500412/
Neuropathic Pain: From Mechanisms to Treatment - PubMed
- DOI: 10.1152/physrev.00045.2019
- 已发布: 2021/01/01
- Keywords: allodynia; immune cells; ion channels; neuropa…
- Authors: Nanna Brix Finnerup
- 页数: 43
Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a common chronic pain condition with major impact on quality of life. Examples include trigeminal neuralgia, painful polyneuropathy, postherpetic neuralgia, and central poststroke pain. Most patients complain of an...Mechanisms of Neuropathic Pain - PMC - PubMed …
2022年3月6日 · Neuropathic pain reflects both peripheral and central sensitization mechanisms. Abnormal signals arise not only from injured axons but also from the intact nociceptors that share the innervation territory of the injured nerve.
Neuropathic pain: Mechanisms and therapeutic strategies
In neuropathic pain, loss of Potassium-Chloride Cotransporter (KCC2) functional expression in spinal cord dorsal horn neurons contributes to GABAergic disinhibition. KCC2 expels chloride ions out of the neurons and hence …
Neuropathic pain: mechanisms and their clinical implications
2014年2月5日 · Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured neurons and along nociceptive and descending modulatory pathways in the central …
- 作者: Steven P Cohen, Jianren Mao
- Publish Year: 2014
Neuropathic pain: Mechanisms and therapeutic strategies
2023年1月16日 · The physiopathology and neurotransmission of pain are of an owe inspiring complexity. Our ability to satisfactorily suppress neuropathic or other forms of chronic pain is …
Neuropathic pain: Etiology, pathophysiology, mechanisms, and ...
2014年1月1日 · There are a number of mechanisms of peripheral neuropathic pain, including peripheral neuronal sensitization, spontaneous ectopic electrical discharges, collateral …
Neuropathic pain: mechanisms and their clinical …
2014年2月5日 · This review focuses on the mechanisms of neuropathic pain, with special emphasis on clinical implications. Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured neurons and along …
Peripheral Mechanisms of Neuropathic Pain—The Role of …
Peripheral neuropathic pain is more common than central neuropathic pain, and is supposed to result from peripheral mechanisms, following nerve injury. The animal models of neuropathic …
Neuropathic pain: diagnosis, pathophysiological …
Examples of neuropathic pain include painful polyneuropathy, postherpetic neuralgia, trigeminal neuralgia, and post-stroke pain. Clinically, neuropathic pain is characterised by spontaneous ongoing or shooting pain and evoked …
Mechanisms of Neuropathic Pain: Neuron - Cell Press
Neuropathic pain reflects both peripheral and central sensitization mechanisms. Abnormal signals arise not only from injured axons but also from the intact nociceptors that share the innervation territory of the injured nerve.
