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    Beta Thalassemia: Types, Symptoms & Treatment - Cl

    Your symptoms will depend on how severe your beta thalassemia is. For instance, you may be asymptomatic (no symptoms) or have mild anemia symptoms with beta thalassemia minor. You may have moderate or more severe symptoms with beta thalassemia intermedia and especially beta thalassemia major.

    Cleveland Clinic

    Beta thalassemia results from a mutation (error) that limits beta-globin production in your body. Hemoglobin consists of four protein chains, two alpha-globin chains and two beta-globin chains. Mutations of the alpha-globin chain cause alpha thalassemia, while mutations of the beta-globin chain cause beta thalassemia. A deficiency of either globin ...

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    The number of defective genes you inherit and the mutation’s location will determine your condition’s severity. Some mutations cause no beta-globin to be produced (beta-zero thalassemia). Other mutations cause too little beta-globin to be made (beta-plus thalassemia). The types of beta thalassemia include the following. 1. Beta thalassemia major (C...

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