Early diagnosis and treatment is associated with a better long-term outcome in anti-NMDAr encephalitis. 19 Given that serological and CSF autoantibody testing can take days to weeks to result, formal diagnostic criteria for probable anti-NMDAr encephalitis does not include autoantibody testing in order to expedite treatment. 20 We recommend ...

Treatment and Prognostic Factors for Long-term Outcome in Patients with Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis: a Cohort Study ; Diagnosis and Significance of Antibody Titers in Anti-NMDA Receptor Encephalitis, a Retrospective Study ; A Clinical Approach to Diagnosis of Autoimmune Encephalitis

2021年8月1日 · In this paper, we review key features of AE, focusing on syndromes involving cell surface and synaptic proteins, and share a practical approach to the diagnosis and management, including common pitfalls associated with nonspecific antibody findings.

Treatment of anti-NMDA receptor encephalitis can vary according to patient, but typically includes a combination of the following: First Line Treatment: Second Line Treatment: Recovery is slow and typically occurs in reverse of symptom onset.

2025年2月12日 · The treatment approach for anti- NMDA receptor encephalitis is considerably different from that used for other psychiatric and neurological conditions. Early recognition, correct diagnosis, and appropriate management of the condition are of vital importance to the prognosis, including reducing mortality rate, admissions to intensive care units ...

2025年1月22日 · We present a case of a 42-year-old male patient diagnosed with anti-NMDAR encephalitis, initially treated with intravenous methylprednisolone (IVMP) and human immunoglobulin (IVIG) without clinical improvement.

Treatment is typically with immunosuppresive medication and, if a tumor is present, surgery to remove it. [1] . With treatment, about 80% of cases have a good outcome. [1] . Outcomes are better if treatment is begun earlier. [2] . Long-term mental or behavioral problems may remain. [2] . About 4% of those affected die from the condition. [2] .

2023年12月11日 · This comprehensive review aims to evaluate the therapeutic potential of bortezomib as a novel therapy for anti-NMDA receptor encephalitis in hopes of mitigating symptoms and improving outcomes for anti-NMDA receptor encephalitis patients.

How is pediatric anti-NMDA receptor encephalitis treated? We see children with this type of encephalitis every year, giving us the experience to recognize and treat this condition. We will use different therapies to suppress the immune system and …

2020年3月26日 · Anti-NMDA receptor encephalitis is an immunotherapy responsive disorder (5). First-line treatment includes immunotherapy agents such as steroids, plasma exchange procedures (PLEX), and intravenous immunoglobulin (IVIg), and the second-line therapy includes B-cell depleting agents such as rituximab (6).