Cell encapsulation is a possible solution to graft rejection in tissue engineering applications. Cell microencapsulation technology involves immobilization of cells within a polymeric semi-permeable membrane .

2013年10月10日 · Encapsulation is one potential strategy to increase viable cell retention while facilitating paracrine effects. Human mesenchymal stem cells (hMSC) were encapsulated in alginate and attached to the heart with a hydrogel patch in a rat myocardial infarction (MI) model.

Cell encapsulation involves the entrapment of living cells such as fibroblasts, myoblasts, embryonic or mesenchymal or neural stem cells [66] engineered to produce a therapeutic molecule within a semipermeable membrane.

Cell encapsulation involves the design and application of specific procedures for immunoisolating cells into appropriate scaffolds. It represents a major advance in cell based therapy as it avoids constraints associated with cell sources, making both allogenic and xenogenic cells putative alternatives to the scarcely available autologous cells.

2014年3月1日 · Cellular encapsulation segregates cells from the surrounding tissue to protect the implanted cell from the recipient's immune system after transplantation. Diverse hydrogel membranes have been popularly used as encapsulating materials and permit the diffusion of gas, nutrients, wastes and therapeutic products smoothly.

1 天前 · 此过程称为单细胞封装（single cell encapsulation）。 所使用的细胞悬液浓度需遵循泊松分布（Poisson law），以确保实验过程中稳定的细胞封装。 本方案可适用于封装不同类型的细胞，并能够生成不同尺寸的液滴。

1 天前 · The anticancer potential of juglone, a naphthoquinone derived from walnut trees, has been extensively studied; however, its hydrophobicity and toxicity obstruct its therapeutic applications. This study aimed to overcome these challenges by encapsulating juglone into poly (lactic-co-glycolic acid) (PLGA) nanoparticles and evaluating their antiproliferative and apoptotic effects on HeLa cells ...

Cellular encapsulation segregates cells from the surrounding tissue to protect the implanted cell from the recipient's immune system after transplantation. Diverse hydrogel membranes have been popularly used as encapsulating materials and permit the diffusion of gas, nutrients, wastes and therapeutic products smoothly.

2020年7月8日 · Encapsulation of islets into immunoisolating/immunoprotective devices provides the potential of abrogating the requisite for lifelong immunosuppression. The field of cellular encapsulation lies at a complex intersection between the areas of chemistry, physics, bioengineering, cell biology, immunology, and clinical medicine.

Encapsulating cells in biodegradable hydrogels offers numerous attractive features for tissue engineering, including ease of handling, a highly hydrated tissue-like environment for cell and tissue growth, and the ability to form in vivo.