Dementia biomarkers -- phosphorylated tau (P-tau181), neurofilament light (NfL), and glial fibrillary acidic protein (GFAP) -- are associated with age, sex, and apolipoprotein E (APOE) ε4 status.

Those findings were integrated with data collected from the participants on cerebrospinal fluid and brain-scan biomarkers of amyloid- β and tau protein, cognitive function, age, sex and Alzheimer ...

Phosphorylation enables tau protein to undergo reversible liquid–liquid phase separation (LLPS), forming micrometer-sized droplets, a property not seen in unmodified tau.

A long-term study reveals how age, sex, genetics, and menopause influence blood biomarkers related to dementia. The study ...

Flagship Pioneering has unveiled a new start-up that aims to find, then drug, targets that are specific to different states ...

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

Abnormal accumulation of tau protein in the brain has been associated ... Findings showed BIIB080 dose-dependently reduced soluble tau biomarkers in cerebrospinal fluid (t-tau and p-tau181 ...