This case demonstrates that isolated optic neuritis in CLL can be effectively managed with corticosteroids and close monitoring, potentially avoiding the need for immediate systemic therapy. The ...

The patient was diagnosed with hereditary ATTR-CM following genetic testing, which revealed the presence of a mutation in the TTR gene. Researchers from India and the US presented the case of a ...

Early identification of IgG4-related renal disease and treatment initiation are key to improving long-term clinical outcomes. Patients with renal involvement in immunoglobulin G4-related disease (IgG4 ...

Hereditary transthyretin (TTR) amyloidosis is an autosomal dominant disorder that presents as transthyretin amyloid polyneuropathy (ATTR-PN), transthyretin amyloid cardiomyopathy (ATTR-CM), or a mixed ...

A case has been reported of anti-CD19 chimeric antigen receptor (CAR)-T cell therapy inducing complete remission in a patient with immunosuppressive therapy (IST)-resistant acquired hemophilia A (AHA) ...

Factors such as ECOG score and methotrexate response more strongly predicted progression-free and overall survival than epilepsy status in PCNSL. Epilepsy in patients with primary central nervous ...

FGFR3-related conditions may be conceptualized as a continuous disease spectrum, rather than a collection of discrete clinical diagnoses. Although achondroplasia and hypochondroplasia are considered ...

Patients with PNH on complement inhibitors are at an increased risk of meningococcal infections and should be appropriately monitored. A teenage girl with a diagnosis of paroxysmal nocturnal ...

The alterations correlated with poorer extremity motor function, and further analysis revealed a link between disrupted lipid metabolism and MS severity. Patients with multiple sclerosis (MS) have ...

Rozanolixizumab led to consistent and clinically meaningful improvements in the Myasthenia Gravis Activities of Daily Living (MG-ADL) score, the Myasthenia Gravis Composite (MGC) score, and the ...

Patients in the intervention group showed a significant reduction in the Beck Depression Inventory-II scores and stability in markers of disease progression. Reducing levels of depression in older ...

Single-cell RNA sequencing revealed heightened immune activation in patients with alloimmunized SAA, paralleling immune responses seen in FNAIT. HLA class I alloimmunization in severe aplastic anemia ...