During the American Revolution, more than in any subsequent U.S. war, doctors played critical roles beyond their medical functions. A key leader at the outset of the war was Dr. Joseph Warren.

The National Academy of Medicine convened a workshop of experts and published a report that reviews the progress generative AI has achieved in health care and discusses future opportunities and ...

Autoimmune generalized myasthenia gravis is a disease that manifests with fluctuating muscle weakness. Inebilizumab is a monoclonal antibody that depletes CD19+ B cells, which are central to ...

The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Throughout the course of multiple sclerosis, gradually progressive neurologic impairment can occur, which has been called disability accrual. Current disease-modifying therapies for multiple ...

Tolebrutinib is an oral, brain-penetrant, and bioactive Bruton’s tyrosine kinase inhibitor that modulates peripheral inflammation and persistent immune activation within the central nervous ...

Recognizing that financially strapped students find their residency choices constrained by cost-of-living considerations, Mass General Brigham began supplementing the salaries of residents in need.

Giant-cell arteritis is a systemic vasculitis with limited treatment options. The efficacy and safety of upadacitinib — a ...