Objectives/Background Based on previous experiences, the Food and Drug Administration and the European Medicines Agency recommend that clinical trials for novel antidiabetic drugs are powered to ...

Correspondence to Dr Shamir R Mehta, Division of Cardiology, Hamilton General Hospital, Hamilton, Ontario ON L8L 2X2, Canada; smehta{at}mcmaster.ca Objective Approximately 10% of patients with ...

BACKGROUND Endothelial dysfunction plays an important role in the development of atherosclerotic vascular disease, which is the leading cause of mortality in patients with chronic renal failure.

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2 School of Medicine, The University of Queensland, Brisbane, Australia 3 Department of Epidemiology and Biostatistics, School of Population Health, The University of Queensland, Brisbane, Australia 4 ...

6 Department of Medicine/Geriatrics and Gerontology Wake Forest University, Winston-Salem, North Carolina, USA 7 Department of Preventive Medicine, Northwestern University, Chicago, Illinois, USA 8 ...

2 Non-Profit Research Association Alliance for the Promotion of Preventive Medicine (APPREMED), Mechelen, Belgium Objective Heart failure (HF) is characterised by collagen deposition. Urinary ...

a Cardiac Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London SW3, UK, b Department of Medical Statistics and Evaluation, Imperial College School of Medicine ...

2 University College London Hospitals NHS Foundation Trust, London, UK Background and aims Mineralocorticoid receptor antagonists (MRAs) reduce mortality and hospitalisation in heart failure with ...

Department of Cardiovascular Medicine, Catholic University Medical School, Rome, Italy Dr Felicita Andreotti, Department of Cardiovascular Medicine, Catholic University, Largo F Vito 1 - 00136 Rome, ...

Background The Assessing cardiovascular risk using Scottish Intercollegiate Guidelines Network (ASSIGN) risk score, developed in 2006, is used in Scotland for estimating the 10-year risk of first ...

Background Cardiopulmonary exercise testing (CPET) is essential for assessing patients with hypertrophic cardiomyopathy (HCM) ...