Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

However, developing therapeutic resistance is one of the significant challenges. Recent research suggested that small interfering RNA (siRNA) has excellent potential as a therapeutic to silence genes ...

The expression of host miRNAs is affected by virus invasion, which also affects virus replication. Increasing evidence has demonstrated that miRNA influences RNA virus multiplication by binding ...

CD Bioparticles recently announced the availability of its new line of Exosome Extraction Kits. NEW YORK, NY, UNITED STATES, February 21, 2025 ...

When, 3 years later, researchers identified a large class of nonprotein coding RNAs called microRNAs (miRNA), they confirmed the potential for large scale endogenous silencing (2–4). As ...

Nanomedicine. 2014;9(16):2545-2555.

The candidate in question is VY9323, an AAV gene therapy combining a highly potent pri-miRNA against superoxide dismutase 1 ...

PORTLAND, IN, UNITED STATES, January 28, 2025 /EINPresswire / -- The RNA based therapeutics has been explored as a promising treatment option for the diseases which are difficult to treat. Development ...

Objective Although the role of microRNA-17 (miR-17) has been identified as a tumour biomarker in various studies, its prognostic value in cancers remains unclear. Therefore, we performed a systematic ...

为解决胰腺癌（PDAC）治疗难题，台北医学大学的研究人员开展 hsa_circ_0004781 在 PDAC 中作用的研究，发现其促癌作用及相关机制。这为 PDAC 治疗提供新靶点，极具科研价值，推荐科研读者一读。

Encouragingly, the concept of miRNA-based therapeutics is developing, with synthetic antagonists of miRNAs (antagomiRs) currently in phase II trials for the treatment of chronic hepatitis C virus ...