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生物通
43 分钟
揭秘 RFX3:开启人类胰岛干细胞治疗糖尿病的新钥匙
为探究调节因子 X3(RFX3)在人类胰岛发育中的作用,研究人员构建 RFX3 基因敲除(RFX3 KO)的诱导多能干细胞(iPSC)模型开展研究。结果发现 RFX3 对胰岛细胞分化至关重要,其缺失影响胰岛功能。这为糖尿病治疗提供新思路。
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