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2025年,全球mRNA疫苗累计接种已超百亿剂次,其高效性与安全性彻底改写了传染病防控的格局。从新冠疫苗到癌症治疗,mRNA技术正以惊人的速度渗透医学领域。然而,回溯至2005年,科学家Karikó团队首次发现,将mRNA中的尿苷(U)替换为假尿苷(Ψ),可显著降低免疫原性,这一发现成为mRNA疗法的“阿基米德支点”。但为何Ψ-RNA能逃避免疫系统的安检?
Arsenale Bioyards recognized the inefficiencies and developed a platform that could radically change biomanufacturing, much like the Bessemer converter in the mid-19th century transformed the steel ...
Sabic to close UK cracker, plastics recycler Novoloop raises funds, Kymera strikes molecular glue deal, and more ...
胰腺导管腺癌(PDAC)是最具侵袭性的癌症之一,其发生发展机制一直是研究热点。最新发表在Nature Cancer的一项研究揭 示了一个关键的表观遗传机制:氧化应激通过NRF2-EZH2信号轴推动胰腺癌前病变向恶性肿瘤的转化。
Food-grade compressor oils, such as those based on polyalphaolefin (PAO) or polyalkylene glycol (PAG) synthetic base stocks, ...
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News-Medical.Net on MSNResearchers uncover how RNA modifications evade immune detectionThe innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self ...
The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component ...
Biopharma company AbbVie will acquire Capstan Therapeutics for up to $2.1 billion in cash, giving it access to promising new ...
COVID-19 has largely dropped out of the headlines, but the virus that causes it is still circulating. We ask what we should know about a new variant of SARS-CoV-2, the state of the COVID-19 pandemic ...
In this edition of Market Factors we’ll list the ways markets are acting contrary to history, and then detail ‘growth at a ...
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
Fueled by Over 13 Million Global Creators, Milestone Reflects Platform Growth, Strategic Positioning, and Accelerating Creator Monetization NEWPORT BEACH, CA / ACCESS Newswire / June 30, 2025 / Amaze ...
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