De novo lipogenesis is associated with the development of human diseases such as cancer, diabetes, and obesity. At the core of lipogenesis lies acetyl coenzyme A (CoA), a metabolite that plays a ...

The Acetyl CoA Carboxylase pipeline drugs market research report outlays comprehensive information on the Acetyl CoA Carboxylase targeted therapeutics, complete with analysis by indications, stage of ...

The Acetyl CoA Carboxylase 2 pipeline drugs market research report outlays comprehensive information on the Acetyl CoA Carboxylase 2 targeted therapeutics, complete with analysis by indications, stage ...

Insufficient acetyl-CoA derails the immune system's ability to protect the body. Until now, however, it was unclear exactly how immune cells maintained their acetyl-CoA reserves.

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists. The findings, ...

Research groups at the University of Greifswald have succeeded in unravelling a fundamental regulatory mechanism of the enzyme Acetyl-CoA synthetase from the bacterium Bacillus subtilis down to an ...

Recent studies have revealed the mechanism by which NO blocks the activity of mitochondrial TCA cycle enzymes, including pyruvate dehydrogenase (PDH), which impacts acetyl-CoA production (27 – 29).

Decision letter after peer review: Thank you for submitting your article "Acetyl-CoA production by select metabolites promotes cardiac repair after myocardial infarction via histone acetylation" for ...

Acetyl-CoA synthetase is an enzyme that catalyzes the production of acetyl-CoA, a molecule that is involved in many cellular functions, including regulation of gene expression. The researchers’ ...

The metabolism-reprogramming marker ketohexokinase (KHK)-A and acetyl-CoA synthetase 2 (ACSS2) phosphorylation at S659 (ACSS2 pS659) play important roles in tumorigenesis and tumor development.