SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

Histone acetylation, the transfer of an acetyl group to lysine residues, changes the charge of histones and favors ... TCA, tricarboxylic acid; ACL, ATP citrate lyase; ACCS2, acyl-CoA Synthetase Short ...

This study shows that MRGPRX2 activation with substance P increased Lysyl t-RNA synthetase (LysRS) translocation to the nucleus ... an enzyme that catalyzes the conversion of pyruvate to acetyl CoA ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...