Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

引言在我们体内，数以亿计的细胞每天都在进行着极其复杂的生命活动，其中翻译过程扮演着至关重要的角色。翻译是基因表达的最后一步，它通过核糖体（ribosome）将mRNA上的遗传信息转化为蛋白质，驱动细胞的功能。然而，尽管翻译过程已经被广泛研究，研究人员却一直未能完全解开一个关键谜团：多个核糖体如何协同工作来高效地 ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins.

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the ...

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get them moving again. Shelby is an assistant editor for The Scientist. She ...

"Ribosomes are very large macromolecular machines that very rapidly and precisely decode mRNA into protein. For a long time, they've been viewed as kind of 'dumb code-reading machines' that don't ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

Ribosomes getting stuck The team also made an important discovery about ribosome collisions—where one ribosome runs into another due to a tricky RNA segment or differences in speed, for example ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...