In autoimmune diseases such as inflammatory bowel disease (IBD), the function of regulatory CD8 T cells (CD8 Treg) is compromised, in part due to the expression of inhibitory KIR receptors ...

Research in horses may eventually lead to a treatment for people who develop blindness as a result of the autoimmune disease ...

A huge turnout was expected for the funeral Sunday of slain Hezbollah leader Hassan Nasrallah, as the Lebanese militant group ...

The NoVo Foundation, the charitable organization controlled by Peter and Jennifer Buffett, gave out at least $45 million to regional organizations, schools, activist groups, farm programs, food ...

A large crowd took to the streets of Berlin on Saturday in opposition to a demonstration staged by around 100 neo-Nazis. More ...

Israeli hostage Shiri Bibas's community confirmed her death Saturday after new remains were returned from Gaza, as the seventh hostage-prisoner exchange under a fragile Gaza ceasefire was set to go ...

Palestinian militants on Saturday freed two Israeli hostages, among the last live captives eligible for release under the ...

We continued our conversation about MercyOne Genesis’s expanding Structural Heart Program with Dr. Devika Kir and Director of ...

The family of Israeli hostage Shiri Bibas confirmed on Saturday receipt of her remains, just ahead of the seventh ...

Lacutamab是一款潜在“first-in-class”的人源化KIR3DL2靶向抗体，能够诱导细胞毒性产生，目前处于治疗CTCL的临床试验阶段。KIR3DL2作为KIR家族的抑制性受体，在正常组织中的表达受到严格限制，但表达于约65%的所有CTCL亚型患者，在某些侵袭性CTCL亚型中（尤其是Sézary综合征患者）表达率可高达90%，而在蕈样肉芽肿和外周T细胞淋巴瘤患者中则约为50%。