The virus particle comes apart, releasing the viral genome. The viral RNA (vRNA) is translated into a single polypeptide that is cut into ten proteins, and the viral genome is replicated.

The RNA polymerase is responsible for the replication of viral genetic material and the activation of viral genes, and is ...

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

Key steps in the life cycle of HCV include entry into the host cell, uncoating of the viral genome, translation of viral proteins, viral genome replication, and the assembly and release of virions.

Scientists have now developed a new technology that has uncovered the underlying mechanism that has enabled them to calculate ...

Discover how a structural breakthrough in the chikungunya virus is opening new avenues for antiviral drug development and ...

To test whether nSMase2 is essential for viral replication, the team inhibited the enzyme by using ... or by knocking down nSMase2 expression using RNA interference. In human cell cultures, ...

NTNU researchers identified an oral antiviral cocktail that blocks enterovirus replication in human cells and mini-organs. The combination, previously tested for safety, showed no adverse effects on ...

These drugs work by inhibiting the viral reverse transcriptase enzyme, preventing the replication of the viral genetic material ... Their importance extends beyond their role in DNA and RNA, as ...

In RNA, cytosine also pairs with guanine ... interfere with DNA replication and induce cell death in rapidly dividing cancer cells or inhibit viral replication. Examples include: 5-Fluorouracil (5-FU) ...

Overall, 4% of the IV group and 6% of the SC group had HIV-1 RNA levels of 50 copies ... INSTIs inhibit HIV replication by preventing the viral DNA from integrating into the genetic material ...