Researchers show that glycoRNAs, uncovered by the lab of Nobel Laureate, Carolyn Bertozzi, can be used to fight cancer.

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

At this point, translation must be terminated, and the nascent protein must be released from the mRNA and ribosome. Termination of Translation There are three termination codons that are employed ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

Ribosomal RNA (rRNA) is a component of the ribosomes, the cellular machinery responsible for protein synthesis. rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and ...

In the Protein Engineering and Evolution ... the role of RNA modifications in cells. With RNA modifications affecting stability, promoting translation, and influencing its location within the ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).