Positive regulation by TFs that are activators is common in eukaryotes. Considering the restrictive transcriptional ground state, it is logical that positive regulation is the predominant form of ...

Therefore, we set out to investigate alternative balancing mechanisms, whose induction must occur faster than transcriptional regulation. An unanswered, but intriguing question, concerns the ...

The researchers used LUHMES neuronal precursor cells, which can differentiate into functional neurons with a high transcriptional ... on neuronal development, regulation, and disorders." ...

In experiments where transcriptional activation was blocked ... "Our findings highlight an unexpected link between gene ...