New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that ...

Deep learning and ATAC-seq uncover noncoding variants linked to gene regulation and disease in human liver cells.

First, Lear's team helped to create tagged transgenic strains for more than 90% of known transcription factors in the fruit fly genome; collaborators at Yale generated tagged transgenic strains ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development.

These TF-specific structural states may direct gene-specific regulatory events; in other words, Mediator—a general transcription factor—may acquire gene-specific functions that are triggered by TF ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

Researchers have found a new role for the transcription factor (proteins that regulate the transcription, or copying, of genes). In the fruit fly, this transcription factor, named Traffic Jam, ...

Learn about Apple Notes' advanced features like audio recording, transcription, and cross-platform access to stay organized.

Significance: In earlier work, investigators from this team and other collaborators used genome-wide association studies to identify the transcription factor responsible for switching off fetal ...