Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

Deep learning and ATAC-seq uncover noncoding variants linked to gene regulation and disease in human liver cells.

A systematic map of pair-wise physical interactions among mammalian transcription factors will enable studies of transcriptional control in development and disease. The specification of cell and ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development.

These TF-specific structural states may direct gene-specific regulatory events; in other words, Mediator—a general transcription factor—may acquire gene-specific functions that are triggered by TF ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family. Genes and Development 29: 48-62. Dai, Q, Andreu-Agullo C, Insolera R, Wong LC, Shi SH and Lai EC ...

Researchers have found a new role for the transcription factor (proteins that regulate the transcription, or copying, of genes). In the fruit fly, this transcription factor, named Traffic Jam, ...