“祖细胞对损伤的反应是感觉受体再生的关键一步，但这一过程在哺乳动物的内耳和视网膜中被阻断。通过了解强制这种阻滞的基因，我们可以推进恢复患者听力和视力的努力，”南加州大学蒂娜和里克卡鲁索耳鼻喉科头颈外科和南加州大学凯克医学院干细胞生物学和再生医学系的助理教授Gnedeva说。

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the ...

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A USC research team discovered that a single genetic signal may be preventing both hearing and vision cells from repairing themselves. By turning off this signal in mice, they triggered cell growth in ...

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study. Researchers focused on a group of interacting genes called the Hippo pathway, which serve as ...

Seven faculty members at Washington University in St. Louis are among the 471 new fellows selected by the American ...

在研究结论和讨论部分，该研究首次全面鉴定了与 AMI 中 Hippo 信号通路相关的生物标志物，包括 NAMPT、CXCL1、GIMAP6 和 GIMAP7，为开发针对 AMI 的靶向治疗提供了理论基础。尽管研究存在一定局限性，如使用的数据集在以往研究中被广泛应用、样本量相对较小等，但研究结果仍具有重要意义。这些生物标志物不仅具有临床诊断潜力，还为深入理解 AMI ...

Department of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China The Hippo/YAP pathway is a signaling pathway that plays an ...