Institute of Biological Chemistry, Academia Sinica, No. 128, Sec. 2, Academia Road, Nankang, Taipei 115, Taiwan Institute of Biochemical Sciences, National Taiwan ...

Figure 5: Age-dependent increase in insoluble tau in P301L (JNPL3) mouse brains. We have reported a transgenic mouse line, JNPL3, expressing human tau with the P301L mutation that develops NFT ...

本研究旨在探讨Fg对tau病理的影响。具体研究Fg在tau P301S 转基因小鼠大脑中的沉积及其与tau蛋白的相互作用，观察其对神经元凋亡、突触损伤等的 ...