*仅供医学专业人士阅读参考我们知道,人类疱疹病毒(HHV)与阿尔茨海默病(AD)风险增加有关,但是这背后的机制我们了解的还很少。转座子(TE)是一类可以在基因组中移动的DNA序列。正常情况下,转座子通常处于沉睡状态,但近年来有研究显示,病毒感染可能会 ...
好书推荐!《动物行为实验指南》电子版pdf,网盘发货《动物行为实验指南》共674页,涵盖了常见的实验动物,如小鼠、大鼠和斑马鱼,详细描述了每一种行为测试的实验设计、测试设备、实验流程、评估指标、预期结果、常见问题及解决方法、数据分析、模型应用与局限性 ...
Detecting toxic forms of tau before they weave into dense thickets of tangles could pave the way for earlier diagnosis and treatment of tauopathies, including Alzheimer’s disease. In the February 10 ...
两个新的磷酸化位点,p-tau262和p-tau356,检测纤维前tau聚集体的形成,并可能作为阿尔茨海默病tau神经原纤维缠结病理的早期生物流体生物标志物。 阿尔茨海默病研究新突破: 来自瑞典哥德堡大学萨尔格伦斯卡学院精神病学和神经化学系等多个单位的研究人员在 ...
A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau. This is the finding of research from the University of Gothenburg, which also offers ...
Dysregulation of correct protein tau homeostasis represents the seed for the development of several devastating central nervous system disorders, known as tauopathies, that affect millions of people ...
This modern characterization of the 3xTg-AD model includes an assessment of impairments in long-term potentiation followed by quantification of amyloid beta (Aβ) plaque burden and neurofibrillary tau ...
来自巴塞罗那自治大学医学系生物化学与分子生物学系神经科学研究所等单位的研究人员,在《Molecular Psychiatry》期刊上发表了题为 “Synaptic vulnerability to amyloid-β and tau pathologies differentially disrupts emotional and memory neural circuits” ...
Introduction: The goal of this study is to explore the pharmacological potential of the amyloid-reducing vasodilator fasudil, a selective Ras homolog (Rho)-associated kinases (ROCK) inhibitor, in the ...
Tau Lewis was born in 1993 in Toronto, Canada, and lives and works in Brooklyn, New York. A self-taught artist, Lewis has crafted her education through communion with peers, like the queer Caribbean ...
The microtubule-associated protein, tau, is the major subunit of neurofibrillary tangles associated with neurodegenerative conditions, such as Alzheimer's disease. In the cell, however, tau ...