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Phosphorylation enables tau protein to undergo reversible liquid–liquid phase separation (LLPS), forming micrometer-sized droplets, a property not seen in unmodified tau.
Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.
The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. "We were surprised to see that people with a father with Alzheimer's ...
The function of Tau protein belonging to microtubule-associated proteins (MAPs) is to stabilize the microtubule network within neuronal axons [26]. Tau protein is considered to play a central role in ...
Summary: New research reveals that people with a father who had Alzheimer’s may be more vulnerable to the spread of tau protein in the brain, a hallmark of the disease. The study followed 243 ...
Department of Neurology, Medical University of Lublin, Poland Department of Clinical Psychology and Neuropsychology, Faculty of Pedagogy and Psychology, Maria Curie-Skłodowska University, Lublin, ...
Results from a decade-long Canadian study reveal women accumulate more of the toxic tau protein associated with Alzheimer’s yet show greater resistance to brain shrinkage, while paternal inheritance ...
The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. We were surprised to see that people with a father with Alzheimer's ...
As previously announced, results from the Phase 1b study showed dose-dependent reductions in soluble tau protein in cerebrospinal fluid (CSF), decreases in aggregated tau pathology in the brain as ...