Phosphorylation enables tau protein to undergo reversible liquid–liquid phase separation (LLPS), forming micrometer-sized droplets, a property not seen in unmodified tau.

Neurofibrillary tangles (NFTs) are neurobiological lesions that are found in brain cells of patients with Alzheimer's disease (AD). They consist of aggregates of abnormally phosphorylated tau ...

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

The function of Tau protein belonging to microtubule-associated proteins (MAPs) is to stabilize the microtubule network within neuronal axons [26]. Tau protein is considered to play a central role in ...

The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. "We were surprised to see that people with a father with Alzheimer's ...

Summary: New research reveals that people with a father who had Alzheimer’s may be more vulnerable to the spread of tau protein in the brain, a hallmark of the disease. The study followed 243 ...

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The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. We were surprised to see that people with a father with Alzheimer's ...

Department of Neurology, Medical University of Lublin, Poland Department of Clinical Psychology and Neuropsychology, Faculty of Pedagogy and Psychology, Maria Curie-Skłodowska University, Lublin, ...