Other therapies aim to reduce tau phosphorylation, the process that makes tau toxic. Researchers are focusing on various new methods of treating Alzheimer's and are making significant strides in ...

In a study published in the Journal of the American Chemical Society, scientists explore how a brain protein called tau changes its behavior when a small chemical group called a phosphate attaches to ...

Researchers have developed a tau-targeting vaccine that could help prevent the progression of Alzheimer’s disease by ...

Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

Three kinases have been strongly linked to the aberrant phosphorylation of tau, cyclin-dependent kinase 5 (CDK5), glycogen synthase kinase 3β (GSK3β) and extracellular signal-regulated kinase 2 ...

The inflammatory response can affect the tau pathological metamorphosis, increasing tau phosphorylation via MAPK kinase pathways and accelerating tangle formation. Extracellular tau can induce ...