Alzheimer’s disease is notorious for robbing individuals of memory and cognitive function. Researchers have struggled for ...

Phosphatase enzymes are challenging to study due to a lack of specific inhibitors. Here, authors develop a chemical-genetic system to inhibit and characterize a major Ser/Thr phosphatase complex ...

Alzheimer's disease is one of the world’s most prevalent brain disorders, being extremely difficult to treat. Alzheimer's ...

The scientists concluded that while the two markers perform similarly, they yield complementary information, and sequential ...

Dementia affects millions of people worldwide, causing a serious impact on the economy and the healthcare system. Alzheimer’s ...

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is an attractive therapeutic target due to its involvement in cancer and neurodegenerative diseases. Researchers from the ...

There's still so much we don't know about Alzheimer's disease, but the link between poor sleep and worsening disease is one ...

Several lines of evidence link metabolic dysregulation to late-life neurodegenerative diseases. The altered glucose metabolism observed in both Alzheimer's disease (AD) and Parkinson's disease (PD), ...

Discover the breakthrough Alzheimer's test that measures tau tangles in blood, simplifying Alzheimer's diagnosis and ...

A preclinical study from Northeastern University has revealed astonishing evidence that psilocybin – the psychedelic compound in magic mushrooms – could possibly repair brain damage caused by head ...

“The p-tau increase in ALS is only seen in blood and not in CSF. This speaks strongly for phosphorylation of peripheral tau in ALS,” he wrote to Alzforum (comment below.) First authors Samir ...