【导读】将免疫检查点阻断疗法（ICB）与化疗相结合有望治疗三阴性乳腺癌（TNBC），但对其机理仍不完全清楚。在这项研究中，团队整合了已发表的和新的单细胞RNA测序（scRNA-seq）数据，研究了接受紫杉醇（PTX）、纳布-紫杉醇（Nab-PTX）以 ...

The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell ...

T follicular helper cells (Tfh cells) are a specialized subgroup within the so-called CD4 + T helper cells in the immune ...

More information: Saumya Kumar et al, Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue, Cell Discovery (2024). DOI: 10.1038/s41421-024-00681-0 Provided ...