The all-new Venom is a hero, and Flash Thompson made Venom a good guy when he used the symbiote as Agent Venom. If Black Cat bonded with a symbiote, she'd likely still fight by Spider-Man's side.

The symbiote's last host was Lee Price/Maniac, but this union didn't last long. After Cletus Kasady killed Price, he absorbed Mania and became more powerful than ever as the Absolute Carnage.