Global Antisense and RNAi therapeutics Market is valued approximately at USD 3.69 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 18.72% over the forecast period ...

Discover how unique circular RNA molecules are transforming liver cancer research to combat this growing health concern.

想象一下，要在人类30亿个碱基对的基因组中，精确地测试成千上万个单一碱基突变的功能，这无异于大海捞针。传统的实验方法一次只能研究几个突变，效率极低，无法满足大规模筛选的需求。要破解同义突变之谜，首先需要一把能够高效、精准地在基因组上“动手术”的手术刀 ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

人类胚胎干细胞（Human embryonic stem cells, hESCs）存在naïve和primed两种多能性状态，二者在表观遗传、基因表达及发育潜能上存在显著差异。尽管naïve和primed hESCs间基因表达网络的差异已被广泛研究 ...

A team of Indian American scientists led by Pallavi Gopal are working to learn more about the dynamics of a protein to help ...

Skyhawk Therapeutics has dosed the first subject in the randomised Phase II/III FALCON-HD trial of the oral small-molecule ...

SKY-0515 is an oral small molecule designed to reduce the production of both huntingtin (HTT) and PMS1 proteins—two key drivers of HD pathology ...

Dynamics are intrinsic to both RNA function and structure. Yet, the available means to precisely provide RNA-based processes with spatiotemporal resolution are scarce. Here, our work pioneers a ...

When mRNA is used to create vaccines, mRNA carries instructions into our cells to build proteins that form part of a virus, such as the spike protein of the Covid virus. The body’s cells make these ...

Havers worked at the agency for 13 years, according to her LinkedIn profile. In the email announcing her resignation, she said she was most proud of the work she and her colleagues accomplished ...