For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...

Spliceosome structures have been investigated extensively in the past decade, but most of the studies have been restricted to ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular ...

The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex Feb 12, 2025 Researchers discover that hnRNPM guards integrity of cellular protein production ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA.

GENETIC researchers in Barcelona have reached a historic milestone, creating the very first map of the spliceosome. A key part of interpreting DNA, the spliceosome helps cells to interpret and ...

The spliceosome must identify the correct splice sites (SS) and branchsite (BS) used during splicing. E complex is the earliest spliceosome precursor in which the 5' SS and BS are defined. Definition ...