Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

An international collaboration between four scientists from Mainz, Valencia, Madrid, and Zurich has published new research in ...

Splicing is catalyzed by a large molecular machine. This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an ...

Advancing development of next-generation precision Antibody Drug Conjugates (ADCs) to address multiple indications across a range of cancer types ...

More information: Yi Li et al, Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates, Cell Research (2025). DOI: 10.1038/s41422-025-01084-w ...

Researchers have identified mutations in the non-coding gene RNU2-2 as a cause of a newly defined neurodevelopmental disorder ...

Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with the U1 small nuclear ribonucleoprotein to accelerate spliceosome ...

For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...

Apr. 16, 2025 — There's a sensation that you experience -- near a plane taking off or a speaker bank at a concert -- from a sound so total that you feel it in your very being. When this happens ...

Several states are reporting cases of measles, a highly contagious viral disease. Both children and adults can get measles. Before going to a clinic or emergency room, it’s important to check with ...