Patients with degenerative diseases that attack skeletal muscle tissues, such as Duchenne muscular dystrophy, may soon benefit from novel stem cell therapies. A study has demonstrated how new ...

Stem cell biology; regeneration; skeletal muscle regeneration and aging; skeletal muscle stem cells and gene therapy; growth factors and signal transduction; mouse molecular genetics; muscular ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions ...

Our research group is investigating the mechanisms that regulate skeletal muscle regeneration, focusing on skeletal muscle stem cells. We are interested in the biogenesis of skeletal muscle stem cells ...

While these cells could significantly improve the success rates of experimental cell therapies in treating skeletal muscle conditions, they are rare and found only in small quantities in skeletal ...

“This study is important because it looks at the types of cells that regenerate broken bones, the skeletal stem cells, and how they, in turn, are affected by aging.” To investigate the molecular ...

The skeleton allows movement, provides support and protection for vital organs and makes blood cells. Skeletal muscles move the bones in the body. The skeletal system is made from bones and joints.

The team, led by Giuseppe Intini, a bone biologist at the University of Pittsburgh, first compared the cell composition of the calvarial suture—which joins the bilateral bones in the roof of the skull ...

Researchers have found that a deficiency of LRP1 in skeletal progenitor cells results in severe and lasting skeletal defects, including joint fusion, malformed bones, and impaired mobility.