MβCD was then added in the continued presence of agrin, causing AChR clusters to fragment and disappear, as revealed by rhodamine‐α‐BT staining. (B) Clusters of 5 μM minimal size were quantitated. (C, ...

Malfunctions at the site of neuromuscular junction (NMJ) of post-injuries or diseases are major barriers to recovery of function. The ability to efficiently derive motor neurons (MN) from embryonic ...

Neuromuscular junction articles from across Nature Portfolio The neuromuscular junction is a specialized synapse between motor neurons and the muscle fibre they innervate. In vertebrates, the ...

Upon approaching the neuromuscular junction its constituent 24 active zones become visible. Each active zone contains two rows of 13 synaptic vesicles (gold) that are docked at the pre-synaptic ...

The neuromuscular junction (NMJ) is the chemical synapse connecting motor neurons and skeletal muscle fibers. NMJs allow all voluntary movements, and ensure vital functions like breathing. Changes in ...

Neuromuscular disorders affect the nerves that control certain muscles in your body. Some examples include amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). Neuromuscular disorders ...

A human self-organizing 2D neuromuscular junction model. Immunofluorescence analysis of the whole dish shows muscle cells (magenta) organized in bundles surrounded by spinal cord neurons (cyan).

Letter Published: 19 December 1959 Post-activation Changes at the Mammalian Neuromuscular Junction J. I. HUBBARD Nature 184, 1945–1947 (1959) Cite this article ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

Unique human neuromuscular junction assay establishes skeletal muscle as a key player in ALS October 18, 2022 01:27 PM Eastern Daylight Time ...