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RNA不仅是遗传信息的载体,还能作为催化分子促进化学反应。尽管目前已知的天然核酶主要催化核酸的断裂与连接反应,但“RNA世界假说(RNA world ...
The RNA World Hypothesis is a concept put forth in the 1960s by Carl Woese, Francis Crick and Leslie Orgel. It proposes that earlier life forms may have used RNA alone for the storage of genetic ...
生物通报道:RNA世界假说,英文为RNA World hypothesis,是科学依据多年的科学研究而提出的一条关于生命科学的理论。其内容为:生命进化的早期,没有蛋白质(酶),某些RNA可以催化RNA的复制——也就是说RNA是唯一的遗传物质,是生命的源头。
在众多假说中,RNA世界假说(RNA world hypothesis)因其能够解释遗传信息存储与催化功能统一而备受关注。然而,这一假说面临一个关键挑战:如何实现RNA的自我复制?虽然已有研究表明RNA聚合酶核酶(ribozyme) ...
Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...
The RNA world hypothesis gains support from the in vitro evolution of a bifunctional ribozyme that can recognize an activated glutaminyl ester and subsequently aminoacylate a tRNA molecule.
BUFFALO, N.Y. — The RNA world theory suggests that life on Earth began with RNA molecules that copied themselves. It’s believed this self-replication eventually gave rise over millions of years to DNA ...
New research at the Salk Institute now provides fresh insights on the origins of life, presenting compelling evidence supporting the RNA World hypothesis. The study, published in Proceedings of the ...
Salk scientists unveil RNA capabilities that enable Darwinian evolution at a molecular scale, ... Fresh Evidence for the “RNA World” Hypothesis Salk scientists unveil RNA capabilities that enable ...
At some point, RNA must have replicated itself before the evolutionary arrival of DNA and proteins, and now we might know how.