SPLICE-neo is the first tool to comprehensively identify and prioritize splicing neoantigens from both DNA splice-site mutations and de novo RNA aberrant splicings. There are two major advances of ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.

Two upgraded versions of GLORI have addressed the issue and enable absolute quantification of m 6 A from ultra-low RNA starting material. News & Views 07 May 2025 Nature Methods Volume: 22, P ...

Discover how unique circular RNA molecules are transforming liver cancer research to combat this growing health concern.

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

Long non-coding RNAs articles from across Nature Portfolio. Atom; RSS Feed; Definition. Long non-coding RNAs (lncRNA) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length ...

A deep-learning model trained on human data reveals that promoter mutations may explain a significant portion of unsolved ...