RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...

在 RNA 结构分析方面，运用了 SHAPE（selective 2′-hydroxyl acylation analyzed by primer extension）和新开发的 Led-Seq（Ligation-Enhanced Double-End Sequence-Based Structure Analysis of RNA）技术。同时，还采用了一种特殊的 tRNA reads ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

5-甲基胞嘧啶（m 5 C）修饰是RNA最普遍的修饰之一。m 5 C修饰通过影响RNA出核、稳定和剪接等过程来参与多种生物学功能。造血干祖细胞为支持生命持续，分化为各种类型的血细胞，是维持血液系统正常功能的核心细胞。造血干祖细胞在发育过程中经历快速的全局 ...

Primer is The A.V. Club‘s ongoing series of beginners’ guides to pop culture’s most notable subjects: filmmakers, music styles, literary genres, and whatever else interests us—and ...

How to Choose a Primer for Oily Skin Do you really need a primer? How to Apply a Primer for Oily Skin Meet The Experts Those with oily or combination skin can especially count on developing ...

From clear to color-correcting options, our favorite primers give eyeshadow a boost. Cheryl Wagemann is a writer and editor covering beauty and fashion. She has tested and reviewed many products ...