There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...
Because infected host cells ordinarily lack RNA-dependent RNA polymerase (RdRp) activity, these RNA viruses encode a replicative polymerase essential for the production of progeny. Such virally ...
hLife聚焦健康科学领域的前沿进展,旨在促进基础研究与临床应用的融合发展。期刊发表与医学相关各研究领域最新成果,学科领域包括(但不限于)病原生物学、流行病学、生理学、免疫学、结构生物学、疾病监测、肿瘤、药物、疫苗和健康政策等。
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
Eukaryotes transcribe much of their genomes, but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo.I suggest that ∼ 90% of Pol II initiation events in ...
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RNA origami: Artificial cytoskeletons to build synthetic cellsWith the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...
Primrose Bio, Inc. ("Primrose"), a company developing proprietary therapeutic manufacturing technologies, announces the ...
The University of Hong Kong has patented RNA polymerase β subunit/RNA polymerase sigma factor RpoD (bacterial) interaction inhibitors reported to be useful for the treatment of gram-positive bacterial ...
Primrose Bio announced a new product to improve the manufacturing on long-template mRNA vaccines. 1 The Prima RNApols ExTend ...
For the first time, researchers have visualized the three-dimensional structure of the Nipah virus's RNA polymerase—the enzyme responsible for copying the virus's genetic material—at molecular ...
Corp. and St. Jude Children’s Research Hospital Inc. have jointly patented compounds acting as caseinolytic protease P (ClpP) (bacterial) activators and RNA polymerase (bacterial) inhibitors and their ...
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