There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

Because infected host cells ordinarily lack RNA-dependent RNA polymerase (RdRp) activity, these RNA viruses encode a replicative polymerase essential for the production of progeny. Such virally ...

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Eukaryotes transcribe much of their genomes, but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo.I suggest that ∼ 90% of Pol II initiation events in ...

RNA synthesis, or transcription, is the process by which RNA is produced using DNA as a template. This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on ...

Primrose Bio, Inc. ("Primrose"), a company developing proprietary therapeutic manufacturing technologies, announces the ...

For the first time, researchers have visualized the three-dimensional structure of the Nipah virus's RNA polymerase—the enzyme responsible for copying the virus's genetic material—at molecular ...

Primrose Bio announced a new product to improve the manufacturing on long-template mRNA vaccines. 1 The Prima RNApols ExTend ...

The University of Hong Kong has patented RNA polymerase β subunit/RNA polymerase sigma factor RpoD (bacterial) interaction inhibitors reported to be useful for the treatment of gram-positive bacterial ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...

Corp. and St. Jude Children’s Research Hospital Inc. have jointly patented compounds acting as caseinolytic protease P (ClpP) (bacterial) activators and RNA polymerase (bacterial) inhibitors and their ...