New research pioneered by The University of Western Australia is shedding light on the intricate dance between proteins, DNA ...

unfolded protein response). RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

Biologists have discovered that disruptions in transfer RNA function can lead to the development of cleft lip and cleft palate.

Researchers have identified cellular factors that regulate the delivery and stability of mRNA to expand the potential of mRNA ...

Enter the anti-CRISPR protein AcrVIB1 ... The simpler and therefore initially expected mechanism would have been to just prevent the guide RNA from binding in the first place," says first author ...

ADAR1’s RNA editing mechanism Researchers ... underscores the essential role of RNA-binding domain 3, a key portion of ADAR1, in maintaining the protein’s activity and stability.

Binding of miR-3036-5p to CYP18A1 can be prevented by an A-to-I RNA editing, thus elevating CYP18A1 expression, decreasing 20E titer, and finally regulating the wing dimorphism of offspring in aphid.

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...