Researchers have identified cellular factors that regulate the delivery and stability of mRNA to expand the potential of mRNA ...

unfolded protein response). RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and ...

Researchers have discovered that 'DEAD-box helicases 54 (DDX54)', a type of RNA-binding protein, is the master regulator that hinders the effectiveness of immunotherapy -- opening a new path for lung ...

A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions like a film editor rearranging scenes from the same footage to create ...

Enter the anti-CRISPR protein AcrVIB1 ... The simpler and therefore initially expected mechanism would have been to just prevent the guide RNA from binding in the first place," says first author ...