BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

While people often turn to meat, dairy, and legumes for their protein intake, a crucial macronutrient that plays a vital role in muscle building, tissue repair, and overall health, fruits can also ...

You do not need to eat meat or cheese to get enough protein. Beans, dairy-free yogurt, and sorghum are a few plant-based protein sources. Consider these options if you are limiting your meat ...

In this study, we developed a novel method, TF-chRDP (Transcription Factor binding Chromatin-associated RNA, DNA, and Protein), which allows for the concurrent capture of these biomolecules in a ...

The increase of GATA19 levels hinders JAZ1 from binding with MYC2, thus activating jasmonate signaling pathway. This study reveals the function of a microRNA as a dual agent in modulating viral ...

Tubes were incubated at RT for 2–3 min, and then centrifuged at 12,000 g for 15 min at 4°C. DNA was removed and RNA was extracted using the RNeasy kit according to the protocol provided (Qiagen). RNA ...

Immunoprecipitation was used to examine the binding of proteins and chromatin immunoprecipitation assay to detect the binding of HIFs with hypoxia response ... SUMOylation is an important ...

Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital and, Harvard Medical School, Boston, Massachusetts 02139, United States ...