As the roles of Dok-3 in different cell types are starting to be unraveled, accumulating evidence suggests that Dok-3 can function, in a context-dependent manner, as both a positive and negative ...

The cyclic AMP/protein kinase A ... to regulatory T cell (Treg) suppression and inflammatory mediators, such as prostaglandins (PGs), adrenergic stimuli, adenosine, and a number of other ligands. A ...

This review focuses on the roles of the transient receptor potential ... signaling that takes place in neurons, glial cells and the blood-brain barrier following ischemic insult.

African trypanosomes are extracellular, blood-borne parasites that mainly rely on glycolysis for their energy metabolism ... that selectively inhibits the enzymatic activity of trypanosomatid (but not ...

While everyone’s blood is made up of the same basic parts, there’s a lot of variety in blood types. Blood is classified into types to ensure that when you donate or receive blood, it is ...

Q4 2024 Earnings Call Transcript February 13, 2025 Operator: Good morning, and welcome to Agios’ Fourth Quarter 2024 ...

(Nasdaq: AGIO), a leader in cellular metabolism and pyruvate kinase (PK) activation pioneering therapies for rare diseases ... s future clinical programs evaluating mitapivat in pediatric patients ...

produced by the endothelium and red blood cells (RBCs). This study aims to investigate whether RIC affects RBC deformability and levels of NO and nitrite in patients with ischemic stroke. Remote ...

Besides this, there are emerging findings that myeloid cells could be involved in tumor angiogenesis. In this article, we address the role of tyrosine kinase inhibitors in tumor immunology by ...

The researchers note that red blood cells also host many more antigens, some of which cannot be categorized easily but still play an important role in human health. In their work, the team looked ...

a synthetic nanoparticle that mimics the oxygen-carrying role of red blood cells. If the RESTORE trial aims to create the lab-grown burger of blood, Doctor is leading an initiative to create its ...