The phosphorylation state of any protein ... factor-β (TGFβ) and bone-morphogenetic protein (BMP) signalling, the DNA-damage response, RNA processing, cell-cycle progression and gene transcription.

Protein Sci. 2018, 27: 1018 - 1037. Harper, TM; Taatjes, DJ. The complex structure and function of Mediator ... Architecture of the human and yeast general transcription and DNA repair factor TFIIH.

solving a decades-long mystery by determining the first structure of the human protein PINK1 bound to mitochondria. First discovered more than 20 years ago, PINK1 is a protein directly ...