Protease‐activated receptors (PARs) play a central role in platelet activation and thrombosis. These G protein‐coupled receptors are activated through proteolytic cleavage, which unmasks a ...

The research team developed antibody fragments called nanobodies and crosslinked these to make ligands to four platelet receptors (GPVI, CLEC-2, FcɣRIIA and PEAR1).

Platelet receptors recognize pathogens and/or pathogen-induced inflammation: Surface receptors enable platelets to bind directly to pathogens, but also to sense proinflammatory molecules.

Integrin receptors allow cells to attach to other cells and to connective tissue which is necessary to form tissues, organs, or even people, for that matter. Researchers at the University of ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Mathur, Neha. (2022, October 17). Investigating plasma signatures of platelet-derived proteins in ...

On October 19, 2022, a new research paper was published in Oncotarget, entitled, “Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed ...

Nplate (Romiplostim) Romiplate: A Genetically Recombinant Protein, Stimulates Platelet Production Via Stimulation of the Thrombopoietin Receptors - Global Drug Insight and Market Forecast 2017-2030 ...

SU11248, a multitargeted receptor tyrosine kinase inhibitor of VEGF and PDGF receptors, demonstrates antitumor activity in metastatic RCC as second-line therapy, a setting where no effective systemic ...

Paolo Lusso, Ph.D., and colleagues describe their findings in a paper titled “Identification of the platelet-derived chemokine CXCL4/PF-4 as a broad-spectrum HIV-1 inhibitor.” ...

Toll-like receptors (TLRs) signaling can play an important role in the OC treatment. TLR activation in immune cells can help activate an effective antitumor response. In this scenario, a new ...

Birmingham Platelet Group delivers breakthrough ‘nanobody’ technology . October 12, 2023: Researchers led by Professor Steve Watson and Dr Eleyna Martin from the Institute of Cardiovascular Sciences ...